Past Symposia

INAUGURAL SYMPOSIUM Pathogenic Mechanisms in Asthma

May 8, 1990
Pathogenic Mechanisms in Asthma


Chairman:   Lawrence M. Lichtenstein, M.D., Ph.D.

                  Solbert Permutt, M.D.



Lipid Mediators

K. Frank Austen, M.D.


Inflammatory Cells in Asthma

Peter M. Henson, BVME-S, Ph.D.


Analysis of the High Affinity Receptor for IgE

Henry Metzger, M.D.


Mechanism of Activation of the Coagulation-Kinin

System and its Assessment in Human Diseases

Allen P. Kaplan, M.D.


IgE and Asthma

Benjamin Burrows, M.D.


Allergies and Asthma

Thomas A.E. Platts-Mills, M.D.


Mechanisms of Airway Hyper-Responsiveness

Jeffrey M. Drazen, M.D.


A Comparison of Individual Cell and Whole Lung Mechanical Properties

Peter T. Macklem, M.D.

2ND ANNUAL SYMPOSIUM Cellular Adhesion Processes


September 20, 1991

Cellular Adhesion Processes


Chairman:  Robert P. Schleimer, Ph.D.

                 Bruce S. Bochner, M.D.




Endothelial Adhesion Mechanisms in Inflammation and Atherogenesis

Michael A. Gimbrone, Jr., M.D.


The Distinctive Functions of Selectins, Integrins, and Ig Family Molecules in Regulation of Leukocyte Interaction with Endothelium

Timothy Springer, Ph.D.


Mechanisms of Cell Adhesion in Allergic Inflammation

Robert P. Schleimer, Ph.D.


Studies of Polymorphonuclear Leukocyte Migration Across Endothelia

Samuel C. Silverstein, M.D.


Diagnosis and Repair of the Cellular Motor

Thomas Stossel, M.D.


Mechanisms and Consequences of Leukocyte-Endothelial Interactions

John M. Harlan, M.D.

3RD ANNUAL SYMPOSIUM Peptides and Airway Diseases


October 2, 1992

Peptides and Airway Diseases


Chairman:  David Proud, Ph.D.




Localization of Regulatory Peptides and Their Messenger RNAs in the Human Respiratory Tract

Julia M. Polak, D.Sc., M.D., FRCPath


Effects of Neuropeptides on the Airway Vasculature

Jan M. Lundberg, M.B., Ph.D.


Nonadrenergic Noncholinergic Innervation of Airway Smooth Muscle

Bradley J. Undem, Ph.D.


Effects of Sensory Neuropeptides on the Airway Mysoca can be Magnified by Infections

Donald M. McDonald, M.D., Ph.D.


Endothelin as a Potential Mediator of Airway Disease

Douglas W.P. Hay, Ph.D.


Kinins as Potential Mediators of Airway Disease

David Proud, Ph.D.

4TH ANNUAL SYMPOSIUM The Role of Cytokines in AllergicInflammation and Asthma


October 1, 1993

The Role of Cytokines in Allergic

Inflammation and Asthma


Chairperson:  Donald W. MacGlashan, Jr., M.D., Ph.D.




Regulation of Induction of the Lymphokine-Producing Phenotype:  Possible Implications for Vaccine Utilization

William E. Paul, M.D.


Mast Cell-Vascular Cell Interactions:  Role of Cytokines

Peter Valent, M.D.


Cytokine Signal Transduction

John W. Schrader, M.B., Ph.D.


Mast Cells as a Source and Target of Cytokines in Allergic and Inflammatory Responses

Stephen I. Galli, M.D.


Immunoregulatory and Inflammatory Function of the Chemokine Proteins:  Roles in Allergy and Asthma

Thomas J. Schall, Ph.D.


Eosinophils and Cytokines

Gerald J. Gleich, M.D.

5TH ANNUAL SYMPOSIUM Allergic Inflammation:Mechanism and Management


October 7, 1994

Allergic Inflammation:

Mechanism and Management


Chairpersons:  Anne Kagey-Sobotka, Ph.D.

                      David Proud, Ph.D.




What are Human Heart Mast Cells For?

Gianni Marone, M.D.


The Mast Cells:  Dynamics and Regulation in Normal and Diseases Human Skin

Beate M. Czarnetzki, M.D.


The Interaction Between Neuropeptides and Nitric Oxide In Inflammatory Reactions in Human Skin In Vivo

John C. Foreman, D.Sc., Ph.D., M.D.


Stimulated Human Mast Cells Generate IL-5 mRNA and Protein:  Modulation by Anti-anergic Drugs

Edward S. Schulman, M.D.


Anti-allergic Drugs: Perspectives and Challenges

Mary Carol Conroy, Ph.D.


Eosinophil Granule Proteins and Anergic Inflammation

Larry L. Thomas, Ph.D.


Changes in Airway Wall Elements Cause Excessive Smooth Muscle Shortening

R. Robert Schellenberg, M.D., FRCPC


Segmental Antigen Challenge and the Immunopharmacology of Anergic Asthma: What I Learned From Larry

Stephen P. Peters, M.D., Ph.D.


An Update on the Nasal Response to Antigen Challenge

6TH ANNUAL SYMPOSIUM Nerves In Inflammatory Disease


October 13, 1995

Nerves In Inflammatory Disease


Chairman:  Bradley Undem, Ph.D.




Remodeling of Mucosal Nerves During Intestinal Inflammation

Ron Stead, Ph.D.


Plasticity of Sensory Innervation of the Airway During Allergen-Induced Inflammation

Wolfgang Kummer, M.D., Ph.D.


Mechanisms of Neuromodulation by Inflammation Mediators

Daniel Weinreich, Ph.D.


Experimental Allergic Plasma Extravasation:  Role of Neurohumoral Interactions

Jay Nadel, M.D.


Neuroregulation of Blood Flow in the Airways

John Widdicombe, M.D.


Neuroregulation of Lymphocyte Function and Immune Response

David Felten, M.D., Ph.D.

7TH ANNUAL SYMPOSIUM The Genetics of Asthma and Atopic Diseases


October 4, 1996

The Genetics of Asthma and Atopic Diseases


Chairman:               David G. Marsh, Ph.D.

Co-Chairpersons:  Kathleen C. Barnes, Ph.D.

                          David Essayan, M.D.




The Human Genome Project:  Bench to Bedside

J. Craig Venter, Ph.D.


The Genetics of Human Disease

Victor A. McKusick, M.D.


Genetic Analysis of Asthma and Other Complex Diseases

David G. Marsh, Ph.D.


Genetics of Asthma-Baltimore

Deborah A. Meyers, Ph.D.


Genetics of Asthma-Chicago

Carol Ober, Ph.D.


Genome-Wide Search for Asthma and Asthma- Associated Traits

William O.C.M. Cookson, M.D.


Gene Therapy-From Here to the Horizon

Michael Blaese, M.D., N.I.H.

8TH ANNUAL SYMPOSIUM Major Advances in Immunology


October 17, 1997

Major Advances in Immunology


Chairperson:            Susan M. MacDonald, M.D.




T Cell Specificity and Tolerance

Philippa Mamlck, Ph.D.


Monoclonal Antibody-Based Therapies

Ellen S. Vitetta, Ph.D.


Danger:  A New View on Immunity

Polly C. Matzinger, Ph.D.


Viruses and the Immune Response

Diane E. Griffin, M.D., Ph.D.


Advances in the Understanding and Treatment of Human Severe Combined Immunodeficiency

Rebecca H. Buckley, M.D.


What Does What to Whom:  How IL-4 and CD40 Regulate the Human & Germline Promoter

Donata Vercelli, M.D.


Anti-IgE as a Therapy for Allergic Disease

Paula M. Jardiew, Ph.D.


DNA Vaccination

Margaret Ann Liu, M.D.

9TH ANNUAL SYMPOSIUM New Therapeutic Approaches to the Treatment of Asthma


October 9, 1998

New Therapeutic Approaches to the Treatment of Asthma


Chairman:  Mark C. Liu, M.D.




Leukotriene Modifying Agent Therapy

Elliot Israel, M.D.


Anti-IgE Therapy

Niroo Gupta, M.D., Ph.D.


Soluble Interleukin-4 Receptor Therapy of Asthma

Jan M. Agosti, M.D.


Anti-CD4 T-Lymphocyte Therapy

Neil Barnes, FRCP


Anti-IL-5 Therapy

Francis M. Cuss, MA, FRCP


Anti-Adhesion Molecule Therapy:  VLA-4

Roy Lobb, Phil.


Phosphodiesterase Inhibitor Therapy

Theodore J. Torphy, Ph.D.


Genetic Vaccination Techniques for the Treatment of Asthma

Anthony A. Horner, M.D.


Neural Pathways in the Treatment of Asthma

Bradley J. Undem, Ph.D.

10TH ANNIVERSARY SYMPOSIUM Pathogenesis of Asthma: Human Studies


October 15, 1999

Pathogenesis of Asthma:  Human Studies


Chairman:  Lawrence M. Lichtenstein, M.D., Ph.D.




Airway Remodeling in Asthma

Jean Bousquest, M.D., Ph.D.


The Role of Rhinoviruses in Asthma Exacerbations

William W. Busse, M.D.


Non-invasive Markers of Inflammation in Asthma

Peter J. Barnes, D.M.DSc., FRCP


Treatment of Asthma With Lidocaine

Gerald J. Gleich, M.D.


Progress at the Interface of Physiology and Genetics

Jeffrey M. Drazen, M.D.


The Pharmacogenetics of B-2 Adrenergic Receptor Polymorphisms in Asthma

Stephen B. Liggett, M.D.


The Bronchial Epithelium as Interfrator of Environmental Signals in Inflammation and Repair Responses in Asthma

Stephen T. Holgate, M.D., DSc


T Cell Activation and Hyperresponsiveness in Provoked Asthma

A. Barry Kay, M.D., Ph.D.


The Immune Response in Inhalant Allergens: Relevance to the Increase in Asthma

Thomas A.E. Platts-Mills, M.D., Ph.D.

11TH ANNUAL SYMPOSIUM Exploring the Etiological Theories Behind the “Asthma Epidemic”


September 29, 2000

Exploring the Etiological Theories Behind the “Asthma Epidemic”


Chairman:  Alkis G. Togias, M.D.




The Influence of Allergens on Asthma Development

Diane Ruth Gold, M.D.


Virus Infections and Type I Immunity in Asthma

Sebastian L. Johnson, M.D., Ph.D., FRCP


Asthma and Air Pollution

C. Arden Pope, Ph.D.


Relevance of the Farming Environment for the Development of Childhood Asthma

Ericka yon Mutius, M.D.


Role of Infection at the Beginning of Asthma: Gene by Environment Interactions

Fernando D. Martinez, M.D.


The Rising Trends Revisited: What are the Factors Contributing to Increasing Asthma?

Thomas A.E. Platts-Mills, M.D., Ph.D.

12TH ANNUAL SYMPOSIUM Biology and Pharmacology ofInflammatory Cell Trafficking


November 15, 2002

Biology and Pharmacology of

Inflammatory Cell Trafficking


Chairman:  Bruce S. Bochner, M.D.




Neutrophil Trafficking in the Lungs During Acute Inflammation

Claire Doerschuk, M.D.


Chemokines and Tissue-Specific Lymphocyte Homing

James Campbell, Ph.D.


Th2 Cell and Eosinophil Trafficking to the Allergic Lung

Andrew Luster, M.D., Ph.D.


T-Cell Migration To and Within Lymph Nodes

Ulrich von Andrian, M.D., Ph.D.


CD33-Related Siglecs: A Major Family of Leukocyte Inhibitory Receptors

Paul Crocker, Ph.D.


Chronic Administration of Alpha 4 Integrin Antagonists in Experimental Autoimmune Encephalomyelitis

Ted Yednock, Ph.D.


Regulation of Integrin Function

Donald E. Staunton, Ph.D.


Latest Developments in the Discovery of Drugs Targeting Chemokine Receptors for the Treatment of Asthma and Allergy

Jose Carlos Gutierrez-Ramos, Ph.D.

13TH ANNUAL SYMPOSIUM The Skin as an Immune Organ


November 7, 2003

The Skin as an Immune Organ


Chairpersons:            Lisa Beck, M.D.

                        N. Franklin Adkinson, Jr., M.D.




The Role of APCs in Cutaneous (Allergic) Inflammation

Thomas Bieber, M.D.


Strange Bedfellows Required in Allergic Contact Sensitivity: NK T Cells and B-1 B Cells

Philip Askenase, M.D.


Antimicrobial Peptides Discovery: Biology and Development Into Therapeutics

Michael Zasloff, M.D.


What Can Animal Models Teach Us About the Pathogenesis of Atopic Dermatitis?

Raif Geha, M.D.


Immunosurveillance and Lymphocyte Trafficking

Thomas Kupper, M.d.


The Type I Cytokine Network in Psoriasis Vulgaris as Defined by Genomic and Therapeutic Studies

James Krueger, M.D.

14TH ANNUAL SYMPOSIUM Functional Genomics of Asthma


November 12, 2004

Functional Genomics of Asthma


Chairperson:  Shau-Ku Huang, Ph.D.




Molecular Genetics of Asthma

William Cookson, M.D.


Gene Array Study of Pulmonary Inflammation

Marc Rothenberg, M.D., Ph.D.


Mast Cell Transcriptome

Hirohisa Saito, M.D., Ph.D.


Proteomics Approach in the Study of Asthma

Alan Scott, Ph.D.


Comparative Genomics and the Identification  of Functional Regions in the Human Genome

Len A. Pennacchio, Ph.D.


Drug Targets Discovery Using Genomics Approach

Flossie Wong-Staal, Ph.D.

15th ANNUAL SYMPOSIUM Immune Regulation, Tolerance and Allergy


November 4, 2005

Immune Regulation, Tolerance and Allergy


Chairperson:  Steve N. Georas, M.D.




Airway Dendritic Cells Regulate Tolerance vs. Immunity at the Host Environment Interface

Bart N. Lambrecht, M.D., Ph.D.


Tryptophan Catabolism: A Pivotal Regulator of Adaptive Immunity

Andrew L. Mellor, Ph.D.


Regulating the Regulators: Tregs and Human Diseases

Ethan M. Shevach, M.D.


Regulatory T Cells and Asthma

Douglas Robinson, M.D.


Food Allergy and the Breakdown of Tolerance

Lloyd Mayer, M.D.


Manipulating Tolerance In Vivo: Lessons From Tumor Immunology

Drew Pardoll, M.D., Ph.D.

16THANNUAL SYMPOSIUM Immunobiology of IgE-bearing Cells


November 10, 2006

Immunobiology of IgE-bearing Cells


Chairperson:  John T. Schroeder, Ph.D.



New Insights into Human Mast Cells that Develop In Vivo

Lawrence B. Schwartz, M.D., Ph.D.


Limited TCR Repertoire and Fulminant Th2/ Eosinophilic  Inflammatory Disease

William E. Paul, M.D.


Dynamic Membrane Interactions during IgE-FceRI Signaling

Barbara Baird, Ph.D.


Role of Syk Tyrosine Kinase in the Development of Allergen-induced Airway Hyperresponsiveness and Inflammation

Erwin Gelfand, M.D


The Resurrection of Eosinophils in the Allergic Arena

Francesca Levi-Schaffer, Ph.D.


Redirecting Dendritic Cell Function Through IgE-FceRI vs. TLR Activation

John T. Schroeder, Ph.D.

17TH ANNUAL SYMPOSIUM The Biology of Epithelia in Immunity


November 16, 2007

The Biology of Epithelia in Immunity


Chairperson:  Cristiana Stellato, M.D., Ph.D.



Bacterial Activation of TLR2 Modulates Epithelial Barrier Function

Alice S. Prince, M.D.


From Epithelial Innate to Adaptive Immune Response:

Crosstalk Between Epithelial Cells and Dendritic Cells

Yong-Jun Liu, M.D., Ph.D.


Bronchial Epithelium in Airway Diseases

Pascal Chanez, M.D., Ph.D.


Lymphocytes and Resolution of Direct Epithelial Lung Injury: Who Knew?

Landon S. King, M.D.


Keratinocyte Defects in Atopic Dermatitis

Lisa A. Beck, M.D.


The Role of Intestinal Epithelial Barrier Function in

Autoimmune Diseases Pathogenesis

Alessio Fasano, M.D.


Mechanisms of Glucocorticoid Responses in Airway Epithelium

Cristiana Stellato, M.D., Ph.D.

18th ANNUAL SYMPOSIUM IgE and IgG Signaling in Human Allergic Diseases


November 21, 2008

IgE and IgG Signaling in Human Allergic Diseases


Chairpersons:            Robert G. Hamilton, Ph.D.

                        N. Franklin Adkinson, Jr., M.D.



Gatekeeper Function of IgE Antibody in Allergy

S. Gunnar O. Johansson, M.D.


IgG Antibodies as Modulators of Allergic Disease

Rob Aalberse, Ph.D.


Recombinant Allergen-Based Diagnosis and Therapy of Allergy

Rudolph Valenta, M.D.


Cytokinergic Activities of Monomeric Human IgEs in

Human Mast Cells

Hannah J. Gould, Ph.D.


CD23: A Natural Regulator of IgE Synthesis

Daniel Conrad, Ph.D.


The FceRI-KIT Axis: Relevance to Clinical Disorders

of Mast Cell Function

Dean Metcalfe, M.D.


Fcg/Fce Targeting Molecules as Therapeutics for Allergic Disease

Andrew Saxon, M.D.



November 20, 2009

        The Airway


Chairpersons:            Landon King, M.D.

            Bruce Bochner, M.D.



Genetics of Asthma: Past, Present and Future

Kathleen C. Barnes, Ph.D.


Autophagy in Lung Disease: Friend or Foe

Augustine M.K. Choi, M.D.


Airway Epithelial Host Defenses: A Key to Regulating Viral Exacerbations of Asthma and COPD?

David Proud, Ph.D.


Dangerous Allergens: New Concepts in Allergic Innate Immunity

Steve N. Georas, M.D.


Inflammatory and Immune Responses in the Upper Airways and Sinuses of Humans

Robert P. Schleimer, Ph.D.


Non-Adherence in Difficult-to-Control Asthma:  Prevalence, Causes, and Interventions

Cynthia S. Rand, Ph.D.


The Role of the Nasal Ocular Reflex in Allergic Rhinoconjunctivitis

Robert M. Naclerio, M.D.


Virus-Induced Asthma Attacks

David B. Jacoby, M.D.

20TH ANNUAL SYMPOSIUM Novel Lessons From Murine Biology of Allergic Diseases


November 19, 2010

Novel Lessons From Murine Biology of Allergic Diseases 

Chairpersons:            Zhou Zhu, M.D., Ph.D

                                   Bruce Bochner, M.D.



IL-17 Family Cytokines: New Players in Asthma

Chen Dong, Ph.D

Basophils as a Non-Redundant Player in Allergy and Protective


Hajime Karasuyama, M.D., Ph.D.

The IL-13 Decoy Receptor Tightly Controls Pathogenic Th17 and

21st ANNUAL SYMPOSIUM Airway Remodeling: From Nose to Lung

21st Annual Johns Hopkins Asthma and Allergy Center Symposium

Airway Remodeling: From Nose to Lung

Friday, November 18, 2011

Johns Hopkins Asthma and Allergy Center Auditorium

5501 Hopkins Bayview Circle, Baltimore, MD 21224


7:30 a.m.-  8:30 a.m.               Registration and Continental Breakfast


8:30 a.m. -  8:45 a.m.              Welcome: Allen C. Myers, Ph.D.


8:45 a.m. – 9:30 a.m.               Charles G. Irvin, Ph.D.

                                                     University of Vermont, Burlington, VT

                                                     “The nose: a window to the asthmatic lung”


9:30 a.m. – 10:15 a.m.             Reynold A. Panettieri, Jr., M.D.          

                                                      University of Pennsylvania Medical Center,

                                                      Philadelphia, PA

                                                      “Steroid Insensitivity: How Does Airway Smooth

                                                       Muscle Contribute?”

22nd Annual SymposiumSkin Responses in Innate and Adaptive Immunity

22nd Annual Johns Hopkins Asthma and Allergy Center Symposium

Skin Responses in Innate and Adaptive Immunity

Friday, November 16, 2012

Johns Hopkins Asthma and Allergy Center Auditorium

5501 Hopkins Bayview Circle, Baltimore, MD 21224


7:30 a.m.-  8:30 a.m.               Registration and Continental Breakfast


8:30 a.m. -  8:40 a.m.              Welcome: Tao Zheng, MD & Sarbjit S. Saini, MD


8:40 a.m. – 9:25 a.m.               Raif Geha, M.D.

                                               Children’s Hospital, Harvard Medical School,     

                                               Boston, Massachusetts

                                     “Mechanisms of Skin Inflammation in Atopic Dermatitis” 


9:25 a.m. – 10:10 a.m.             Amy S. Paller, M.D.

                                                Northwestern University, Feinberg School of 

                                                Medicine, Chicago, IL

                                      “Epidermal Barrier Defects in Atopic Dermatitis”

23rd Annual Johns Hopkins Asthma and Allergy Center SymposiumCough: Pathophysiology and Emerging Therapeutic Strategies

Friday, November 22, 2013


Johns Hopkins Asthma and Allergy Center Auditorium

5501 Hopkins Bayview Circle, Baltimore, MD 21224



8:30 a.m. - 8:55 a.m.               Registration and Continental Breakfast


8:55 a.m. - 9:05 a.m.               Welcome:  Brendan J. Canning, Ph.D.


9:05 a.m. - 9:45 a.m.               Peter V. Dicpinigaitis, M.D.

                                                Albert Einstein College of Medicine, Bronx, NY

                                                “Evaluation and Management of Chronic Cough”


9:45 a.m. - 10:35 a.m.             Kathryn M. Edwards, M.D.

                                                Vanderbilt University, Nashville, TN

                                                “Pertussis: Its Role in Cough Illness”


10:35 a.m. - 11:00 a.m.           Coffee Break


11:00 a.m. - 11:40 a.m.           Jacky Smith, Ph.D.

                                                University of Manchester, Wythenshawe, UK

Below is a complete listing of all past symposia. You may click on the list on the left to see a particular year.  Note that there was no symposium held in 2001.